Synthesis of deuterium labelled chloroquine, hydroxychloroquine and their metabolites

Lei Tian; Chi Zhang; Jian Li

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Synthesis of deuterium labelled chloroquine, hydroxychloroquine and their metabolites

Author(s): Lei Tian, Chi Zhang and Jian Li*

This paper describes the synthesis of deuterium-labelled chloroqiune, hydroxychloroquine and their metabolites. Mass spectrometry analysis of these compounds revealed over 98% deuterium enrichment

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