Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 7

ZrO2 nanopowder catalyzed one-pot green synthesis of Hantzsch 1,4-dihydropyridine derivatives under dry media


A mild, general, convenient, and efficient one-pot synthesis of 1,4-dihydropyirdines(1-5) is described using conventional heating, and microwave irradiation(1-5) have been synthesized from ethyl-3-oxo-3-phenylpropanoate, ammonium acetate and respective substituted benzaldehydes catalysed by ZrO2 nanopowder in dry media under microwave irradiation . The structure of the synthesized compounds was characterized by FT-IR, MS, elemental analysis, 1H NMR and 13C NMR spectral studies.