Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 5

Wound healing activity of Capparis zeylanica (root)


The methanol extract of Capparis zeylanica Linn. root was evaluated for its wound healing potential in two different types of wound models viz., incision and excision. Two dose levels (100, 200 mg/kg b.w.) of methanol extract of Capparis zeylanica root were tested by incision wound model. The 100 mg/kg produced mild wound healing activity whereas 200 mg/kg produced pronounced healing properties in the tested parameters, tensile strength and DNA content. Two concentrations, 1% and 2% were tested in the excision wound model. There was better healing property observed in 2% concentration when compared to povidone iodine ointment. It was confirmed by finding the parameters; percentage wound contraction, epithelisation time, collegen content and DNA content