Water pollution is one of the major global environmental problems. It is an acute problem almost in all major rivers and water reservoirs in India. Water pollution is increasing and becoming severe day-by-day and posing a great risk to human health and other living organisms. There is growing concern on the deterioration of ground water quality due to geogenic and anthropogenic activities. Present investigation aims at insight about the level of contaminants of surface water, groundwater and sediment analysis of selected locations of Pavana river of Pimpri- Chinchwad area of Pune district. An attempt has been made to assess the water quality, sediment and weed analysis of the samples. A higher value of TDS was observed at groundwater site G4 with 834.27 mg/l while it was lower at surface water site 1 by 65.12 mg/l. Dissolved oxygen content of the water samples was observed quite well in limit but it was lower with 1.6 mg/l at surface water site 4 while higher at surface water site 2 with 5.23 mg/l. In the present study, highest value of COD was observed by value of 120 at surface water site S4 while was lowest with only 64 mg/l at groundwater site G4. As expected groundwater samples showed higher values of hardness content as compared to surface water samples of Pavana river. Nickel content was found to be present at all sites with a range of 22 to 40 mg/kg. There is urgent need for more representative samples to be used to go beyond preliminary assessment as reported in the present study for making appropriate recommendations.