Arsenic is a kind of necessary trace elements of livestock and poultry nutrition, and plays an important role in the tissues and organs and metabolism, etc. With the rapid development of feed industry, the organic arsine preparations of feed additives have been widely applied in animal husbandry. But these organic arsine preparations are absorbed less in animal body, and large amount of them are directly discharged by the animal dung. The animal dung which contains a lot of arsenic is not harmlessly managed, and it has polluted the environment and endangered human health. The types, mechanism of action and applications of the organic arsine are briefly introduced in this paper. The toxicological effects, the harm to human and ecological environment, and the related treatment measures of the organic arsine are mainly reviewed. We put forward to forbid entirely the use of organic arsine preparations in feed industry as soon as possible.