Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 7

The effects of lentil hydro alcoholic extraction blood parameters in mice


Lentil with the generic name of Securigera securidac has many therapeutic effects. One of the most important is the strengthening of hematopoiesis. In this study, the effects of lentils hydro alcoholic extract on hematological parameters in l mice (Balb/C) were investigated. This study was conducted in 5 groups of 40 mice. The control group received no extract, Placebo group Received 5 cc normal saline every other day and 3 treated group is injected lentil extract with doses 50,100,200 mg/kg/2day intraperitoneally (IP). Then the mice blood samples were taken from the heart, the main evaluated parameters, were the number of red and white blood cells, Hemoglobin, HCT, MCHC ،MCH and MCV with respect of controlled groups. The results with SPSS software at P<0.05 were analyzed. Results showed that at all doses the number of red blood cells, hemoglobin and MCHC increased, while the MCH and MCV showed no significant difference. The number of white blood cells at doses of 100 and 200 mg / kg increased. Results shows that the dose dependent effect of lentil on blood parameters in mice.