Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2021 Vol: 13 Issue: 7

Synthesis, Spectroscopic and Antimicrobial Studies of Cu (II) and Fe (III) Complexes of Heterocyclic Schiff Base Ligand


In the presence study synthesis, characterization and antimicrobial studies of newly synthesized Cu (II) and Fe (III) Complexes from heterocyclic Schiff base ligand. The new Schiff base ligand was synthesized by condensing chalcone 1-(2-hydroxy-3-nitro-5-methyl acetophenone)-3-(2-hydroxy phenyl) with phenyl hydrazine hydrochloride in the ethanolic medium. From this ligand new transition metal complexes of Cu (II) and Fe (III) with a Schiff base ligand 3-(2-hydroxy-3-nitro-5-methyl phenyl)-5-(2-hydroxy phenyl)-1-phenyl-â??2-pyrazoline were synthesized and characterized on the basis of elemental analysis, H1 NMR, IR, Mass, Electronic spectra and Molar conductance data. IR spectral data shows that ligand acts as monobasic ONdonor towards both Cu (II) and FE (III) ions. The antimicrobial activities of these complexes were screened against S.aures, S.pyrogenes, E. coli and S.typhe pathogens which are heretofore too unknown.

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