Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 6

Synthesis of trimetazidine hydrochloride impurity B by conventional method


The aim of work was to synthesis 1,4-bis(2,3,4-trimethoxybenzyl)piperazine, i.e. Impurity B of Trimetazidine hydrochloride, Impurity was synthesized in a very conventional method and structural interpretations were done by NMR and HPLC

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