Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2010 Vol: 2 Issue: 4

Synthesis of some substituted hydroxytriazenes and their analgesic activity


In the present study the hydroxytriazene compounds were synthesized and the purity of each hydroxytriazene was checked by I.R. studies and physical characteristics. The synthesized hydroxytriazenes were screened for there analgesic activity. The analgesic study was performed by tail immersion method and acetic- acid induced writhing test. The results of the study indicate that the parent hydroxytriazene compound does not show analgesic activity where as other substituted hydroxytriazene compounds showed significant analgesic activity in both experimental models