Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 7

Synthesis of some new 1,4-dihydropyrimido[1,2-a]benzimidazoles and evaluation of their biological activity


Synthesis of a series of pyrimido[1,2-a]benzimidazo les (4a-j) was achieved from acetoacetamides, name of aldehyd e and benzimidazole using refluxing with DMF and iso lated by methanol with high yield and purity. The pyrimido[1,2-a]benzimidazoles of the products were supported by FTIR, PMR and mass spectral data.