A simple, fast and accurate method has been developed for the determination of (MAPIMP)2Zn by High Pressure Liquid Chromatography. The analysis was carried out on Waters 2695 separation module HPLC system with Waters 2487 Dual wavelength Absorbance detector. The column used was a stainless steel column of dimension 15 cm x 4.6 mm, packed with octadecylsilane bonded to porous silica ( Make : Neosphere 120-5-C18 Altima column is suitable ).The detector used was Ultraviolet ( UV ) detector. The validation of proposed method was also carried out.