Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 5

Synthesis of pyrazolo [3,4-b] pyridines using basic ionic liquid [bmIm]OH

Abstract

Basic ionic liquid catalyzed synthesis of various pyrazolo [3, 4-b] pyridines were synthesized by cyclocondensation of 5-amino-3 aryl -1-H phenylpyrazoles, p-substituted benzoylacetonitriles and some aryl aldehydes by using basic ionic liquid, [bmIm]OH. It acts as a base catalyst. Comparative study of triethylamine and [bmIm]OH. and ammonium acetate was studied .Reusability of catalyst with good yields under green reaction conditions is the salient feature of this synthetic method.