Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 6

Synthesis of polycyclic heterocycles through domino Knoevenagel intramolecular hetero Dielsâ??Alder reaction under solvent free and microwave irradiation conditions

Abstract

Benzopyrano-pyrano-pyrazoles were synthesized through domino Knoevenagel intramolecular hetero Diels–Alder reaction under solvent free and microwave irradiation conditions. These compounds have the potential to exhibit biological activity. A high degree of chemoselectivity was achieved by the application of microwave irradiation. This green chemistry protocol showed to be very useful under milder reaction conditions.

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