Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 3

Synthesis, characterization and antimicrobial studies of a pentadentate Schiff base ligand and its Copper (II) complexes

Abstract

A pentadentate Schiff base ligand (H3L) was synthesised from 1,3-diaminopropan-2-ol and 2’-hydroxy-5’- methylacetophenone and a series of copper(II) complexes were synthesised using H3L and copper(II)precursor complexes of substituted benzoic acids. The synthesized complexes have been characterized on the basis of elemental analysis, molar conductance and spectroscopic studies such as UV-Visible and FT-IR. All the synthesized complexes and the Schiff base ligand were screened for their in vitro antibacterial activities against Proteus mirabilis, Enterococcus faecalis, and Escherichia coli and antifungal activities against Aspergillus niger, Aspergillus flavus and Candida albicans by well diffusion method. In addition, the antioxidant activities were also done for all the complexes