Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2018 Vol: 10 Issue: 6

Synthesis, Characterization, and Biological Activities of 4â??-(1H-Benzimidazol-2-yl)-2, 2â??:6â??, 2â??â??-terpyridine and its Copper Complex


Terpyridine derivatives and their metal ion complexes have many applications in the fields of supramolecular chemistry, medicinal chemistry and material science. There has been only a few studies on 4’ heteroaryl substituted – 2, 2’: 6’, 2’’ – terpyridines and their metal ion complexes which may be useful as pharmacological agents. In recent years there has been considerable interest in developing 4’- substituted terpyridines and their metal complexes as anticancer drugs, anti-oxidants and as antimicrobials.

synthesized (a) 4’-(1H-benzimidazole-2-yl)- 2,2’:6’,2’’ – terpyridine (bitpy) was incorporated with copper perchlorate finally this complex was characterized by elemental analysis, IR, UV-visible and 1H NMR, and cyclic voltammetry. Application of this complex also were  studied.