Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 7

Synthesis and thermal study of 1,2,4-triazole derivatives


A series of 1,2,4-triazole derivatives (PM4a-c) were synthesized and characterized by various analytical tools such as FT-IR, NMR, mass spectrometry and elemental analysis. The thermal stabilities of these compounds (PM4a-c) were also investigated by TGA and DSC analysis. Moreover, the kinetic parameters such as order of reaction (n), energy of activation (Ea), pre-exponential factor (A), entropy of activation (DS#), enthalpy of activation (DH#) and Gibbs free energy of activation (DG#) were evaluated using Freeman-Carroll method.