The hydrazone Schiff base ligand, Furo-(phenyldimethine)-carbohydrazone, L was synthesized by reacting terephthalaldehyde with 2-furoic acid hydrazide in 1:2 molar ratio and binuclear complexes of type, [M2L (DMF)4 (CH3COO)4 ] were synthesized by reaction of Schiff base ligand, L with Co(II), Ni(II), Cu(II) and Zn(II) acetates. The Schiff base and its complexes have been characterized on the basis of the results of elemental analysis, molar conductance, magnetic susceptibility measurements and spectroscopic studies viz, FT-IR, 1H NMR, UV-Vis, mass and EPR. The infrared spectral data suggested that the hydrazone Schiff base behaved as tetradentate ligand with ON NO donor sequence towards metal ions. The characteristic resonance signal in 1H NMR spectrum indicated the presence of azomethine group as a result of condensation reaction. Magnetic moment data and reflectance spectra of Co(II), Ni(II), Cu(II) complexes revealed an octahedral geometry around metal ions with distortion in Cu(II) coordination complex. Low conductance value of Zn(II) complex in DMSO indicated its non electrolytic nature. Schiff base, L and its Zn(II) complex have been screened for their antibacterial (Escherichia coli, Methicillin resistant Staphylococcus aureus , Pseudomonas aeruginosa, Streptococcus pyogenes and Klebsiella pneumoniae ) and antifungal activities (Candida albicans, Aspergillus fumigatus, Penicillium marneffei and Trichophyton mentagrophytes (recultured). Complex show more activity than free Schiff base.