Synthesis and in vitro bioevaluation of 1,5-Bis(5-substituted benzimidazole) alkanes as antileishmanial agents

Mahesh Verma; Anil Bh; ari; Rajesh Kumar Nema

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2010 Vol: 2 Issue: 3

Synthesis and in vitro bioevaluation of 1,5-Bis(5-substituted benzimidazole) alkanes as antileishmanial agents

Abstract

Some 1,5-bis(5-substituted benzimidazole)alkanes (4a-4f, 5a-5f & 6a-6d ) were synthesized from 3a-3f substituted benzimidazole and screened towards in vitro antileishmanial activity profile. Some of compounds such as 4c, 5c, 6c & 6d displayed good antileishmanial activity.

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