Mixed ligand complexes of transition metal with 8-quinolinols and 5-Alkoxumethyl-8-quinolinol have been prepared. Structural, spectroscopic and thermal properties have been studied on the basis of infrared spectra, Mass spectra, NMR spectra, electronic spectra, and elemental analyses. Also their antibacterial activities against Gram – ve (Escherichia coli and Ps. Aeruginosa Bacillus subtilis) and Gram +ve (Becillus megaterium and S.taphylococcus aureus) and antifungal activities again Aspergillus niger and Trichothesium Sp. have been carried out. All the tested complexes show higher antibacterial activity as compared to free ligand.