Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 5

Synthesis and characterization of some novel Pyrimidines via Aldol Condensation


The synthesis and characterization of some novel Pyrimidine derivatives have been presented. Acylation of resorcinol followed by nuclear prenylation with isoprene gives Chroman. Chroman on treatment with p-substituted benzaldehydes affords substituted chalcones. Pyrimidines have been prepared from chalcones by condensing with Guanidine hydrochloride in alkali medium. The structure of Pyrimidines has been characterized by spectral analysis.