This article involve synthesized of β-lactam compounds from amine derivatives .The first step prepared of azo compounds from 4,4-diamino diphenylsulphon (DDS) with 3-methoxy-4-hydroxybenzaldehyde (Vaniline) .Then prepared of Schiff base from azo compound with 4-aminoantipyrine. This compounds ware characterized by melting point, FT.IR,1H NMR and C13NMR