Synthesis and biological investigation of novel 1,3-di(substituted azol)-2-(substituted hetrocycles (substituted aryl)methylene)propane-1,3-dione derivatives as antifungal agents

Santosh N. Mokale

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 12

Synthesis and biological investigation of novel 1,3-di(substituted azol)-2-(substituted hetrocycles (substituted aryl)methylene)propane-1,3-dione derivatives as antifungal agents

Abstract

A novel series of1,3-di(substituted azol)-2-(substituted hetrocycles (substituted aryl)methylene)propane-1,3-dione derivatives were synthesized and tested for their in vitro antifungal activity. These compounds showed moderate activity against strains of Aspergillus species and Candida albicans by Agar diffusion method.