Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2010 Vol: 2 Issue: 4

Synthesis and Biological Evaluation of Some Novel Chromene-2-one Derivatives for Antipsychotic Activity


Various Chromene -2- one derivatives (1a-1f) were synthesized and evaluated for antipsychotic activity. All the synthesized compounds showed antipsychotic activity with muscle relaxant property. The compound 1d, N-(Fluoro benzothiazol-2-yl)-(4-Methyl-2-oxo-chromene-7-yloxy) acetamide has been found to have significant atypical behaviour.