The present paper deals with the synthesis and characterization of metal complexes of new Schiff base derived from Pramipexole(4,5,6,7-Tetrahydro-N6-propyl,2,6-benzothiazolediamine). The bidentate ligand is derived from the inserted condensation of pramipexole with O-hydroxy benzaldehyde (OHB) in a 1:1 molar ratio. Using this bidentate ligand, complexes of Cu(II), Ru(II) with general formula ML2 have been synthesized. The synthesized complexes were characterized by several techniques using Elemental analysis, IR, NMR, UV-VisSpectrometry, ESR, Vibrational spin magnetometry, TG-DTA and Conductometric measurements. The elemental analysis data suggest that stoichiometry to be 1:2[M:L].All the complexes are non electrolytic in nature as suggested by molar conductance measurements. Infrared spectral data indicate the co-ordination between ligand and central metal ion through de protanated Phenolic oxygen and azomethine nitrogen. In addition the authors have been screened the compounds for biological activity. It was found that the compounds have shown activity against the organisms like Salmonella typhi, Enterococcus faecails and Escherichia coli.