Synthesis and antioxidant activity of disubstituted 1,3,4-oxadiazoles, 1,3,4-
thiadiazoles and 1,2,4-triazoles

A. Padmaja; C. Rajasekhar; A. Muralikrishna; V. Padmavathi

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

Reach Us

+44 1625708989

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2012 Vol: 4 Issue: 1

Synthesis and antioxidant activity of disubstituted 1,3,4-oxadiazoles, 1,3,4- thiadiazoles and 1,2,4-triazoles

Abstract

Some new disubstituted 1,3,4-oxadiazoles / thiadiazoles and 1,2,4-triazoles were synthesized by cyclocondensation of arylsulfonylethylsulfonylacetic acid methyl ester and benzylsulfonylethylsulfonylacetic acid methyl ester with different nucleophiles. All the new compounds were evaluated for antioxidant activity. The compound 8c exhibited greater antioxidant activity.