Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 5

Synthesis and antimicrobial evaluation of N-aryl substituted-1,3,4-thiadiazolidin 2-amines


A series of variousN-aryl substituted-1,3,4-Thiadiazolidin 2-amines were synthesized bythe reaction All the compounds werecharacterizedby their melting point, solubility against organic solvents, TLC, IR, and1H NMR spectral. All the synthesized compounds were tested forantimicrobial and anti fungal activity.(Staphylococcus aureus (MTCC96), Escherichia coli (MTCC 443)Aspergillusniger (ATCC16404) and Candida albicans (ATCC10231).