Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 3

Synthesis and antimicrobial activity of pyrazine carboxamide derivatives


A series of pyrazine carboxamide derivatives was synthesized by the condensation of pyrazine-2-carboxylic acid chloride with various substituted amino pyridines. The structures of these derivatives were elucidated on the basis of IR, 1H-NMR and mass spectral data. These compounds were further evaluated for their antimycobacterial activity and antifungal activity