Original Articles: 2012 Vol: 4 Issue: 2
Synthesis and Antibacterial Activity of Zn(II) Complexes with 2-substituted Benzothiazoles and Amino Acids
Abstract
In the present study we report the synthesis and antibacterial activity of Zn(II) complexes with 2-substituted benzothiazole ligands {2-(2´-hydroxyphenyl) benzothiazole(HPBT), 2-(2´-mercaptophenyl) benzothiazole (MPBT),1,2-bis(2-benzothiazole) ethanol (BBTE), 1,2-bis(2-benzothiazole)ethane thiol (BBTET) as primary ligand & with some amino acids (leucine and valine). Structure of the synthesized complexes was established on the basis of IR, 1H NMR & elemental analysis. All these complexes are coloured, thermally stable and non electrolytic in nature. The ligands and their metal complexes were tested against pathogenic bacteria, namely Staphylococus aureus (+ve) and Escherichia coli (-ve). The results indicate that the metal complexes are found more active than the parent ligands.