Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 4

Sulphamic acid assisted synthesis of polyhydroquinolines via Hantzsch multicomponent reaction: A green approach

Abstract

A Facile and efficient one pot, four component synthesis of polyhydroquinoline derivatives via the Hantzsch condensation reaction using sulphamic acid as heterogeneous catalyst by green approach is described herein. The present methodology offers several advantages such as Excellent yields, economy of cost and time, absence of side products and operational simplicity, ecofriendly, recyclability and reusability of the catalyst are some of the salient features of this reaction.

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