Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 9

Studies on some organic molecules containing ligand and sulfa drug moieties

Abstract

The condensation reaction between 4-(((5-(ethoxycarbonyl)furan-2-yl)methyl)(methyl)amino)-2-hydroxybenzoic acid and Sulphanilamide was give 2-hydroxy-4-(methyl((5-(4-sulfamoylphenylcarbamoyl)furan-2-yl)methyl)amino) benzoic acid (HMSPCFMAB). The novel ligand was characterized by elemental analysis and spectral studies. The transition metal chelates viz. Cu2+, Ni2+ , Co2+ , Mn2+ and Zn2+ of HMSPCFMAB were prepared and characterized by metal-ligand (M:L) ratio, IR and reflectance spectroscopes and magnetic properties. The antifungal activity of HMSPCFMAB and its metal chelates was examined against various fungi.