NaY zeolites were added into cut tobacco and filter tip of a commercial brand of cigarettes substitute for activated carbon. Cigarettes with NaY zeolite were prepared and smoked in a smoking machine and the mainstream smoke was collected. The effect of NaY zeolite was investigated on the release of benzo[a]pyrene(B[a]P) and phenol in flue-cured cigarette mainstream smoke. The results showed that the removal efficiency of NaY zeolite added into cut tobacco was clearly higher than that added into filter tip for reducing B[a]P and phenol in cigarette mainstream smoke.