Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 6

Studies on Carica Papaya Starch as a Pharmaceutical Excipient


A study has been carried out to investigate the physicochemical, binding and disintegrating properties of starch isolated from grains of Carica papaya (Family: Caricaceae). The studies indicated that this starch is qualitatively and quantitatively comparable to Corn starch as also the rheological and swelling characteristics. Paracetamol (500mg) tablets prepared using Corn and Carica papaya starch met the requirements of uniformity of weight, assay, friability and hardness. These tablets also conformed to the disintegration and dissolution specifications of Indian Pharmacopoeia. Carica papaya starch showed adequate binding and disintegrating characteristics.

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