Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 3

Stability evaluation of lipid nanocapsules in parenteral nutritional mixture


Olive and soybean oils are commonly used in parenteral nutrition. Lipid NanoCapsules based on vegetal oils (vo-LNC) can be used to allow both an easy dispersion of the oily phases in water and an improvement of parenteral mixture stability. To evaluate the stability of vo-LNC by size measurement, we chose to inspire us from the storage conditions and measurement intervals of the guideline of international conference on harmonization (ICH); stability testing of new drug substances and products Q1A(R2). Results showed that the size of vo-LNC was stable which allows safe administration by parenteral use.

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