Olive and soybean oils are commonly used in parenteral nutrition. Lipid NanoCapsules based on vegetal oils (vo-LNC) can be used to allow both an easy dispersion of the oily phases in water and an improvement of parenteral mixture stability. To evaluate the stability of vo-LNC by size measurement, we chose to inspire us from the storage conditions and measurement intervals of the guideline of international conference on harmonization (ICH); stability testing of new drug substances and products Q1A(R2). Results showed that the size of vo-LNC was stable which allows safe administration by parenteral use.