Simple, sensitive and precise spectrophotometric me thods have been developed for the estimation of valacyclovir, aceclofenac, racecadotr il, valdecoxib, nebivolol and reboxetine in bulk and pharmaceutical dosage forms. Methanol and triple distilled water were used as solvents for the estimation of all these drugs. Absorption maxima of all the above drugs were determined and the estimations were carried out in tablet dosa ge forms. Results of the analysis were validated statistically and by recovery studies.