Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

header
Reach Us reach to JOCPR whatsapp-JOCPR +44 1625708989
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2015 Vol: 7 Issue: 3

Spectrophotometric determination of Tiopronin based inhibitory effect on hemoglobin

Abstract

A highly simple and sensitive catalytic spectrophotometric method for the determination of tiopronin based on its inhibitory effect on the hemoglobin-catalyzed the reaction of H2O2 and acid chrome blue K(ACBK) was developed. The concentration of tiopronin is linear with the percentage inhibition (I%) of system under the optimal experimental conditions. The calibration graph is linear in range 0.05 to 2 mg/L with the detection limit of 8.5μg/L. The relative standard deviation was 4.1 % for 11 determinations of 1.5 mg/L. This method can be used for the determination of tiopronin in pharmaceutical preparations with satisfactory results.

http://sacs17.amberton.edu/

rtp slot demo