Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 11

Sonochemical synthesis of 2-arylbenzimidazoles using amberlite IR-120 Resin

Abstract

simple, efficient and ecofriendly method for one pot synthesis of 2-arylbenzimidazoles has been developed in acetonitrile using ultrasound and amberlite IR-120 resin at room temperature. Experimental results showed that ultrasound induced amberlite IR-120 resin efficiently synthesized substituted 2-arylbenzimidazoles (96 – 68 %) and recyclable up to five times without loss of activity. The method provides several advantages such as green solvent, simple work-up procedure, shorter reaction time and higher yield.