Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 3

Skeletal muscle relaxant activity of methanolic extract of Rumex nepalensis in albino rats


The objective of the present study was to evaluate the skeletal muscle relaxant activity of methanolic extract of the leaves of Rumex nepalensis (MERN) using Rota-Rod method. MERN was administered orally at dose of 400mg/kg to Wistar Albino rats. The methanolic extract significantly reduces the fall off time (motor coordination), and highly significant (**P<0.01) at 30min of duration. Thus, the result suggested that the MERN possess skeletal muscle relaxant activity may be due to presence of different chemical compounds present in the extract.

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