The comparative studies of secondary metabolites investigation used in pharmacognostic drug research using qualitative test is been performed on Cassia occidentalis leaf as well as stem ; belongs to family Ceasalpinieaceae.This plant is of high economic value due to the presence of antioxidant and antimicrobial activity. The samples extracted using various solvents like Ethanol, Methanol, Ethyl acetate and water to detect the presence of active components. The phytochemical screening revealed the presence of carbohydrate glycosides, alkaloids, phenols, flavanoid, aminoacid, coumarine and phytosterols. Since it contains high proportion of phenols and alkaloid, it is reliable to possess antioxidant and anticancer activity.