Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 3

Screening for antifungal activity of medicinal and aromatic plants is another way to valuing the Moroccan Arganeraie

Abstract

To preserve the argan forest, and develop its surrounding ecosystem, our study aims to evaluate the antifungal activity of 107 plant species, harvested in different regions of area of argan tree, against 20 strains of clinical isolates of species of Candida (C) as following, C.albicans (12), C. dubliniensis (1), C. glabrata (4) and C. krusei (3) which have shown some degree of resistance to conventional antifungal and levied on patients with clinical suspicion of nosocomial candidiasis in hospital. The in vitro antifungal activity of 101 EO and 21 FO extracts of aromatics and medicinal plants including 26 endemic species and they distributed among 73 genera and 31 families, with Lamiaceae being the most represented, was determined using the agar diffusion method. Our results showed that among the 107 plants screened, 82.24% have shown an activity expressed in inhibition diameter ranging from 16 mm to over 30 mm. The area of argan tree is a supplier of aromatic and medicinal plants with potent antifungal activity with potential practical applications in the treatment of nosocomial infections and should be tested in vivo in the future. These natural products represent a sustainable alternative to the use of chemical antifungals.