Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2010 Vol: 2 Issue: 2

Schiff�¢����s bases of piperidone derivative as microbial growth inhibitors

Abstract

Piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko Piperidone synthesis which involves combining a alkyl-1, 3-acetonedicarboxylate with benzaldehyde and an amine. This multicomponent reaction reaction related to the Hantzsch pyridine synthesis.Some 4-piperidones give very good antimicrobial activity. So, here are some substituents of 4-piperidone to check whether I t give same activity or not.