Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

header
Reach Us reach to JOCPR whatsapp-JOCPR +44 1625708989
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2013 Vol: 5 Issue: 10

Schiff base complexes derived from thiosemicarbazone, synthesis characterization and their biological activity

Abstract

The Schiff bases anisaldehyde thiosemicarbazone (ATC), 3-4, dimethoxy benzaldehyde thiosemicarbazone (DMBTC), thiophene-2 aldehyde thiosemicarbazone (TATC), 2-acetyl pyridine thiosemicarbazone (APTC) and acetyl acetone thiosemicarbazone (AATC) were prepared by standard methods and characterized by M.P. & I.R. Spectra. Their complexes with palladium {(Pd ATC), (Pd DMBTC), (Pd TATC), (Pd APTC), (Pd AATC)} ruthenium {(Ru ATC), (Ru DMBTC), Ru (TATC), (Ru APTC), (Ru AATC)} and rhodium {(Rh ATC), (Rh DMBTC), (Rh TATC, (Rh TATC), (Rh APTC), (Rh AATC)} have been prepared by standard method and characterized by elemental analyses, electrical conductance, magnetic susceptibility, IR and electronic spectral studies molar conductance. Both the ligands and their complexes have been screened for their fungicidal & bactericidal activities and the results indicate that they exhibit significant antimicrobial properties.