The chemistry of glucosylamine derivatives has gotten among the synthetic compounds noticeable consideration as of late inferable from its significance in the pharmaceutical field. Glucosylamines carrying (R)-homoallylamines, benzoimidazole, phenanthrolineringshavebeenrepresente to display a wide range of pharmacological activities, which incorporates antibacterial, antimicrobial, antioxidant, anti-HIV and anticancer activity. These observations have been guiding for the synthesis of different derivatives of these glucosylamine derivatives enclosing biologically active nuclei and concentrate their pharmacological activities.