Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Reviews: 2017 Vol: 9 Issue: 10

Review on Fe-Catalyzed Carbon-Carbon, Carbon-Heteroatom Oxidative Coupling Reactions: En route to Heterocycles

Abstract

Iron-catalyzed oxidative coupling between two C-H bonds, and C-H with heteroatom-H bonds have received significant attention due to its atom-economy, and sustainable nature. Oxidative coupling and annulations strategy provide step-economy route towards the synthesis of heterocycles. This review highlights the Fe-catalyzed C-C and C-heteroatom oxidative coupling reactions and its potential application in the synthesis of heterocycles, bioactive natural products.