Objective: To analyze the causes of knee injuries football players to explore the effect of the system of rehabilitation measures applied in these patients functional recovery of the knee. Methods: June 2012 June 2013 knee injury 70 cases occurred football player, according to the principles of randomized into experimental group and control group, the control group received conventional treatment regimens, on the basis of conventional therapy group system rehabilitation, compared two groups of patients recover knee condition, knee function was. Results: The effective treatment of patients in the experimental group was 97.14%, significantly higher than 82.86%, knee functional status of patients in the experimental group than the control group, P <0.05, statistically significant results. Conclusion: The combination of injuries in football player’s rehabilitation treatment system can significantly improve the therapeutic effect, enhance knee function is recommended in the clinical application.