Quantitative structure-activity relationship study of parasubstituted trans- and cis-tamoxifen derivatives

JosÃƒÆ’Ã‚Â© C. Barros; Magaly G. Albuquerque; Joaquim F. M. da Silva; Octavio A. C. Antunes

Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2010 Vol: 2 Issue: 4

Quantitative structure-activity relationship study of parasubstituted trans- and cis-tamoxifen derivatives

Abstract

A novel quantitative structure-activity relationship model for para-substituted trans- and cistamoxifen derivatives is proposed, showing correlation with experimental activities. This model represents an improvement to the reported one.