Dengue viruses are the causative agents of dengue fever (DF) and dengue hemorrhagic fever. Dengue virus belongs to family Flaviviridae, having four serotypes that spread by the bite of infected Aedes mosquitoes. It causes a wide spectrum of illness from mild asymptomatic illness to severe fatal dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), dengue fever can be controlled by the number of herbal formulation which can be easily obtained from the nature and also low cost and free from any side effects. Home remedies are used for treatment of dengue fever like Neem leaves and Papaya juice etc.