Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 11

Preparation, characterization and synthesis of silver nanoparticles by using phyllanthusniruri for the antimicrobial activity and cytotoxic effects

Abstract

Silver nanoparticles are nanoparticles of silver, i.e. silver particles of between 1 nm and 100 nm in size. While frequently described as being 'silver' some are composed of a large percentage of silver oxide due to their large ratio of surface-to-bulk silver atoms.Silver nanoparticles are the most prominent one. Silver nanoparticles are nanoparticles of silver, i.e. silver particles of between 1 nm and 100 nm in size and have attracted intensive research interest. It is generally recognized that silver nanoparticles may attach to the cell wall, thus disturbing cell-wall permeability and cellular respiration. The nanoparticles may also penetrate inside the cell causingdamage by interacting with phosphorus and sulfur containing compounds such as DNA and protein. Generally, silver does not adversely affect viable cells and does not easily provoke microbial resistance. Hence silver containing materials were also employed in textile fabrics, as food additives, and in package and plastics to eliminate microorganisms. Because of such a wide range of applications, numerous methods concerning the fabrication of silver nanoparticles, as well as various silver-based compounds containing metallic silver (Ag0) have been developed.Silver nanoparticles (AgNPs) have emerged as an arch product from the field of nanotechnology.