Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 5

Preparation and biological evaluation of c derivatives

Abstract

Preparation and biological evaluation of 7/8/9-Substituted - 10 – N-[(carboxymethyl)-sulfanylacetyl]-phenothiazine - 1 - carboxylic acids. 7/8/9-Substituted 10-N-[bis (2-chloroethyl/diethyl)-amino]-methylphenothiazine- 1-carboxylic acidshave been prepared by the reactionof different substituted phenothizines, dichloroethylamine, diethylamine, and formaldehyde in acidic medium.