Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 8

Polyethylene glycol (PEG-400) as an efficient and recyclable reaction media for the synthesis of substituted 4-(1-aryl-2-nitroethyl)-3-methyl-1H-pyrazol-5- ol in catalyst free conditions

Abstract

Polyethylene glycol (PEG-400) was found to be an effective reaction medium for the one-pot synthesis of 4-(1-aryl- 2-nitroethyl)-3-methyl-1H-pyrazol-5-ol derivatives in good yields under mild reaction conditions. The use of PEG- 400 makes this method low cost, recyclable, and eco-friendly.