Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 7

Polyethylene glycol (PEG-400) as an efficient and recyclable reaction media for one-pot synthesis of simple and straight forward synthesis of 2,4-substituted quinazolines in catalyst free conditions

Abstract

Polyethylene glycol (PEG-400) was found to be an effective reaction medium for one-pot synthesis of quinazoline derivatives in good yields under mild reaction conditions. The use of PEG-400 is low, recyclable, and eco-friendly solvent